010 - The connecting role of COVID-19 vaccine with comorbidity and physical exercise on recovery time among the patients: A moderated mediation path

Background: The purpose of the study was to explore patient recovery time association through inference of physical exercise mediator part and moderator role of COVID-19 vaccine.
Methods: Survey sample size was 659 COVID-19 positive patients who received treatment either at home or in hospitals in Dhaka city, Bangladesh. A cross-sectional study data was collected from May to August 2021. Statistical analysis was performed to assess the potential relationship, and the mediation effect was obtained from a bootstrap approach (n=5000) with SPSS version 26.
Result: Two process models (4 and 58) were tested to investigate the association. The mean age of the patients was 38.43 years (SD=13.89) counting males (39.8%) and females (60.2%). Mediation model 4, using physical exercise (M) as mediator variable, total effect (effect= 0.0778, t =2.1932, P < 0.05), and direct effect (effect= 0.0728, t =2.0643, P < 0.05) of existing comorbidity (X) on recovery time (Y) that was significant, but bootstrap indirect effect was insignificant [impact= (0.0050), BootLL 95%CI (-0.0007) - BootUL 95%CI (0.0128)]. Next, moderated process model 58, comorbidity (X), physical exercise (M) is associated significantly (p<0.05) but the moderator variable Covid-19 vaccine (W) was found insignificant (p>0.05), and interaction was significant [t=1.9873, p<0.05, 95%Confidence Interval (C.I.) =0.0005-0.0983]. Furthermore, conditional effects of focal predictor at values of moderator Covid-19 vaccine who not taken was significant [effect=-0.0494, P<0.05, 95% C.I.= -0.0815 to -0.0173]. Nevertheless, an indirect effect of the bootstrap re-sampling method included value of zero and moderated mediation negative index (-0.009), indicating insignificant association with moderated mediation model of the hypothesis.
Conclusion: Results suggest that moderated mediation model analysis may be effective to reduce curative time among Covid-19 affected patients by maintaining regular physical exercise and vaccination who did not receive.

COVID-19 vaccine

Moderated mediation

Bootstrap

Process model

Comorbidity and physical exercise

Bangladesh 

Mid-Level

Influence

International Conference on Health Policy Statistics 2023