Abstract Number:
3007
Submission Type:
Contributed Abstract
Contributed Abstract Type:
Poster
Participants:
Anahita Saeedi (1), Bruce Barton (2), Raji Balasubramanian (1)
Institutions:
(1) University of Massachusetts, Amherst, Amherst, MA, USA, (2) University of Massachusetts Medical School, Worcester, MA, USA
Co-Author(s):
First Author:
Presenting Author:
Abstract Text:
Background: The Dietary Intervention Study in Children (DISC) clinical trial was designed to shed light on pediatric cardiovascular health's response to interventions over three years.We re-analyzed the original data using advanced statistical methods.Objectives: We aimed to reassess DISC data with linear mixed-effects models and splines, examine treatment effects across subgroup and analyze compliance effect on dietary outcomes.Results: Employing B-splines, effectively minimized the AIC for LDL analysis.The intervention lowered the average LDL by -2.32 (p-value: 0.027).Increased attendance at intervention sessions was significantly associated with a reduction in fat intake (p<0.0001).This effect varied by gender, being less pronounced in girls(p : 0.003).Furthermore, children from families with higher parental education and marital stability were more likely to attend sessions, subsequently influencing dietary outcomes(p-values:0.044, 0.017).Conclusions: Our reanalysis highlights the importance of adherence in pediatric dietary interventions for cardiovascular health. It reveals gender differences and sociodemographic impacts, suggesting tailored dietary strategies are needed.
Keywords:
Dietary Intervention
|Pediatric Cardiovascular Health
|Linear Mixed Effects Models|Spline Models|Compliance Analysis|
Sponsors:
Section on Statistics in Epidemiology
Tracks:
Disease Prediction
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