Abstract Number:
3547
Submission Type:
Contributed Abstract
Contributed Abstract Type:
Poster
Participants:
Chary Akmyradov (1)
Institutions:
(1) Arkansas Children's Research Institute, Little Rock, Arkansas
First Author:
Presenting Author:
Abstract Text:
This poster details a retrospective cohort study conducted at a single center, analyzing 33 patients (11 receiving Bethanechol treatment, 22 controls) hospitalized from 2017 to 2022. The study examines the effect of Bethanechol on individuals with Tracheobronchomalacia (TBM) and bronchopulmonary dysplasia. A case-control match (1:2 ratio) factored in gestational age, sex, TBM and bronchopulmonary dysplasia severity, and respiratory support. The primary focus was Bethanechol's impact on the Pulmonary Severity Score. Unique to this study, Bethanechol administration dates varied over a 105-day period for each case. The poster will display various statistical approaches used to navigate the study's complexities, with a particular emphasis on advanced visualization techniques that clarify the treatment's time-dependent effects. A comparison and discussion of different statistical methods will also be featured.
Keywords:
case control|mixed model|longitudinal|data visualization|clinical study| dependent
Sponsors:
Biometrics Section
Tracks:
Longitudinal/Correlated Data
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