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Bethanechol's Impact on Pulmonary Severity: A Longitudinal Case Control Study

Abstract Number:

3547

Submission Type:

Contributed Abstract

Contributed Abstract Type:

Poster

Participants:

Chary Akmyradov (1)

Institutions:

(1) Arkansas Children's Research Institute, Little Rock, Arkansas

First Author:

Chary Akmyradov
Arkansas Children's Research Institute

Presenting Author:

Chary Akmyradov
Arkansas Children's Research Institute

Abstract Text:

This poster details a retrospective cohort study conducted at a single center, analyzing 33 patients (11 receiving Bethanechol treatment, 22 controls) hospitalized from 2017 to 2022. The study examines the effect of Bethanechol on individuals with Tracheobronchomalacia (TBM) and bronchopulmonary dysplasia. A case-control match (1:2 ratio) factored in gestational age, sex, TBM and bronchopulmonary dysplasia severity, and respiratory support. The primary focus was Bethanechol's impact on the Pulmonary Severity Score. Unique to this study, Bethanechol administration dates varied over a 105-day period for each case. The poster will display various statistical approaches used to navigate the study's complexities, with a particular emphasis on advanced visualization techniques that clarify the treatment's time-dependent effects. A comparison and discussion of different statistical methods will also be featured.

Keywords:

Sponsors:

Biometrics Section

Tracks:

Longitudinal/Correlated Data

Can this be considered for alternate subtype?

Yes

Are you interested in volunteering to serve as a session chair?

Yes

I have read and understand that JSM participants must abide by the Participant Guidelines.

Yes

I understand that JSM participants must register and pay the appropriate registration fee by June 1, 2024. The registration fee is non-refundable.

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