Abstract Number:
3574
Submission Type:
Contributed Abstract
Contributed Abstract Type:
Speed
Participants:
Muzi Na (1), Samidha SudhakarShetty (2), Xiaoyue Niu (3), Stefanie Hinkle (4), Cuilin Zhang (5), Xiang Gao (6)
Institutions:
(1) Pennsylvania State University, N/A, (2) Montana State University, N/A, (3) Penn State University, N/A, (4) University of Pennsylvania, N/A, (5) National University of Singapore, N/A, (6) Fudan University, N/A
Co-Author(s):
First Author:
Muzi Na
Pennsylvania State University
Presenting Author:
Abstract Text:
Despite the plausible mechanisms, how gestational sleep behaviors and the development of sleep disorders influence fetal growth trajectory has not been fully explored. Analyzing the prospective cohort data from the multicenter NICHD Fetal Growth Studies - Singletons (2009-2013), the study included 2,458 pregnant women recruited between 8-13 gestational weeks and followed up to five times during pregnancy. The trajectory of estimated fetal weight (EFW) from 10 – 41 weeks of gestation was derived from three ultrasonographic measures. Linear mixed effect models were applied to model the EFW in relation to self-reported sleep and RLS exposures, adjusting for age, race and ethnicity, education, parity, pre-pregnancy body mass index category, infant sex, and prepregnancy sleep-napping behavior. From enrollment to near delivery, pregnant women's sleep duration and nap frequency declined and RLS symptoms frequency increased generally. Our data do not support an association between gestational sleep behaviors and RLS symptoms and fetal growth between 10-41 weeks of gestation in healthy pregnant women.
Keywords:
time-varying exposures|linear mixed effect models|estimated fetal weight|restless keg syndrome|gestational sleep|cohort study
Sponsors:
Biopharmaceutical Section
Tracks:
Longitudinal Analysis
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