Sunday, Aug 4: 2:45 PM - 2:50 PM
3574
Contributed Speed
Oregon Convention Center
Despite the plausible mechanisms, how gestational sleep behaviors and the development of sleep disorders influence fetal growth trajectory has not been fully explored. Analyzing the prospective cohort data from the multicenter NICHD Fetal Growth Studies - Singletons (2009-2013), the study included 2,458 pregnant women recruited between 8-13 gestational weeks and followed up to five times during pregnancy. The trajectory of estimated fetal weight (EFW) from 10 – 41 weeks of gestation was derived from three ultrasonographic measures. Linear mixed effect models were applied to model the EFW in relation to self-reported sleep and RLS exposures, adjusting for age, race and ethnicity, education, parity, pre-pregnancy body mass index category, infant sex, and prepregnancy sleep-napping behavior. From enrollment to near delivery, pregnant women's sleep duration and nap frequency declined and RLS symptoms frequency increased generally. No significant differences were observed by sleep-napping group or by RLS status between 10 – 41 weeks. Since week 30, small, but statistically insignificant, divergence in the mean EFW was observed by sleep-napping groups. However, our data do not support an association between gestational sleep behaviors and RLS symptoms and fetal growth between 10-41 weeks of gestation in healthy pregnant women.
time-varying exposures
linear mixed effect models
estimated fetal weight
restless keg syndrome
gestational sleep
cohort study
Main Sponsor
Biopharmaceutical Section