Mediation Analysis of High-Dimensional Exposures and Mediators
Thursday, Aug 7: 9:15 AM - 9:35 AM
Topic-Contributed Paper Session
Music City Center
Mediation analysis has been instrumental in uncovering the pathways through which exposure variables impact health outcomes via intermediate variables, or mediators, in environmental studies. When dealing with numerous environmental exposures, such as chemical mixtures or pollutants, alongside multiple potential mediators like metabolites, advanced methodologies are required to effectively disentangle direct and indirect effects. In this paper, we propose a novel method designed for this purpose and evaluate its performance against existing approaches through simulation studies and an application to real-world data.
mediation analysis
high dimensional mediation
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