The Association of Body Mass Index, Health-Related Quality of Life and Survival in Older Patients wi

Music City Center 

The relationship between body composition and bladder cancer outcomes is complex. Higher Body Mass Index seems to predispose to the development of bladder cancer, though the impact on survival is more convoluted. We sought to study this relationship in a cohort of older patients with bladder cancer.
We included patients from the Surveillance, Epidemiology, and End Results-Medicare Health Outcomes Survey database with bladder cancer diagnoses. We assessed demographic, bladder cancer characteristics and treatments, BMI, overall survival, and health-related quality of life (measured by the physical and mental component summary scores and activities of daily livings). The final cohort consisted of 8013 patients with a mean age of 77.6 ± 7 years, 85.6% white and 74.8% males.
Our findings suggest a dual role of BMI in older patients with bladder cancer: higher BMI provides a survival advantage, with improved survival for those who are overweight, obese, or severely obese when compared to those in the healthy range or underweight. Overweight patients also exhibited the highest physical and mental component summary scores, indicating better quality of life. In contrast, severely obese

Bladder Cancer

Survival Analysis

Physical and Mental Component Summary Scores

Body Mass Index 

Section on Statistics in Epidemiology