Statistical Analysis of CKD Progression and Postoperative Outcomes in Total Ankle Arthroplasty

Music City Center 

Chronic kidney disease significantly influences outcomes in total hip and knee arthroplasty, yet its impact on total ankle arthroplasty (TAA) remains understudies. This analysis leverages statistical models to investigate the relationship between CKD progression and postoperative outcomes in TAA.

Using the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) database, we identified all primary TAA cases performed between 2006-2021 in US. Univariable and Multivariable regressions were developed to evaluate the association of CKD stages with length of hospital stay, unplanned return to the operating room, and total postoperative complications. Model diagnosis was performed to confirm the robustness of the results.

675 patients were with different CKD stages. Univariable analyses reveal significant differences in anesthesia type, diabetes, postoperative, dialysis, ASA class, BUN, etc. Significant associations were found between CKD stages and prolonged hospital stays, increased odds (OR=2.18) of unplanned return to room, higher rate of complications (OR=1.85), etc. Our methods facilitated a nuanced understanding of these complex relationships.

CKD stage

TAA

Latent variable

Multivariable regressions

Odds ratios 

Section on Medical Devices and Diagnostics