31: BioPred: an R package for biomarkers analysis in precision medicine

Music City Center 

The R package BioPred offers a suite of tools for subgroup and biomarker analysis in precision
medicine. Leveraging Extreme Gradient Boosting (XGBoost) along with propensity score weighting and A-learn-
ing methods, BioPred facilitates the optimization of individualized treatment rules (ITR) to streamline subgroup
identification. BioPred also enables the identification of predictive biomarkers and obtaining their importance
rankings. Moreover, the package provides graphical plots tailored for biomarker analysis. This tool enables clin-
ical researchers seeking to enhance their understanding of biomarkers and patient population in drug develop-
ment.

precision medicine

subgroup identification

predictive biomarker identification

casual inference 

Biopharmaceutical Section