33: PM2.5 Speciation Chemical Interactions and Neonatal Respiratory Distress Syndrome (RDS)

Music City Center 

After linking the Florida de-identified birth records data to PM Speciation chemicals data, logistic regression analyses were conducted to assess associations between maternal exposure to PM2.5 speciation metals during pregnancy and the risk of neonatal respiratory distress syndrome (RDS), adjusting for various covariates. Study findings highlight the multifaceted nature of RDS risk, reaffirming known risk factors such as preterm birth, low birth weight, and maternal health conditions. Complex interactions among pollutants and maternal health factors were observed, emphasizing the importance of considering synergistic effects in risk assessment. Additionally, race and ethnicity were significant moderating factors, with nuances observed in Hispanic subgroups. Maternal demographics, pregnancy complications, and maternal PM2.5 pollutant exposure affect risk of RDS through complex interactions. Targeted interventions that reduce exposure to harmful pollutants, particularly among high-risk populations, may mitigate RDS burden.

respiratory distress syndrome (RDS)

PM2.5 speciation chemicals

air pollutants

particulate matter

metals

interactions 

Section on Statistics in Epidemiology