Exposure to Personal Care Products and Endocrine-Disrupting Chemicals in SELF

Thomas M. Menino Convention & Exhibition Center 

Exposure to endocrine-disrupting chemicals (EDCs), including parabens, phthalates, and phenols through personal care products (PCPs) has been linked to adverse health outcomes. Using data from the Study of Environment, Lifestyle and Fibroids (n=434), we conducted an exploratory analysis of 31 urinary EDC biomarkers and self-reported recent (24-hour) and long-term (12-month) PCP use. Associations were analyzed using log-normal accelerated failure time models including season and product-by-season interactions. Recent and long-term use of nail, skincare, and makeup products were associated with higher urinary paraben and phenol concentrations. Sunscreen use was associated with benzophenone-3, particularly in summer compared with winter, reflecting seasonal use. Overall, use of several PCPs was associated with higher urinary EDC concentrations, with associations influenced by season and frequency of use. This work was supported by the NIH and NIEHS. Contributions by NIH authors are Works of the United States Government. The findings and conclusions do not necessarily reflect the views of the NIH or the U.S. Department of Health and Human Services.

Epidemiology

Exploratory analysis

Endocrine disrupting chemicals

Personal care products

Season analysis

Accelerated failure time model 

Caucus for Women in Statistics and Data Science