18A: Microplastics: Health Effects and Mechanisms of Toxicity

Matthew Tymchak, MS Moderator
Gradient
Boston, MA 
United States of America
 
Mike Peterson, DABT, ATS Presenter
Gradient
Leavenworth, WA 
United States of America
 
Andrew Yeh, DABT Co-Presenter
Dow Chemical Company
Seattle, WA 
 
Thu, 9/18: 10:45 AM - 11:45 AM CDT
Education Session 
Westin Galleria Houston 
Room: Galleria II 
CM Credit Hours:

Description

Every week, new studies are published that document the presence of micro- and nanoplastics (MNP) in human and animal tissue. However, it is difficult for consumer goods manufacturers and stakeholders to understand and interpret the science regarding the potential human health effects of these substances. Due to their complex physical properties, such as size, shape, and morphology, and chemical properties, such as polymers, additives, and surface chemicals, applying existing toxicological paradigms to MNP toxicity is complicated. Understanding these unique challenges will help product stewards anticipate potential risks associated with product portfolios and may help guide sustainability efforts.

The first part of this session will examine the state of the science in relation to MNP toxicity, with a focus on categorizing the diverse toxicity literature into similar study groups, such as in vitro, animal, and human studies, and using case studies to illustrate the strengths and limitations of each category. The second part of the session will evaluate what existing toxicological paradigms for particles and fibers might teach us about the toxicological mechanisms of action for MNP, especially via inhalation exposure.

Learning Objectives

Upon completion, the participant will be able to:
• Communicate examples and implications of the strengths and limitations of toxicological studies that have been conducted to date with MNP, with a focus on those associated with consumer products.
• Discuss existing toxicological paradigms that describe mechanisms by which particles and fibers can impact human health and how these paradigms inform the potential toxicity of MNP.
 

Product Stewardship Competencies

Toxicology

Certified Professional Product Steward Domain Alignment

Domain I: Assessment, Impact Analysis, & Risk Management

Interactivity and Engagement

Polling
Q&A
Quiz

Content Level

Advanced